Delivery of the gene encoding the tumor suppressor Sef into prostate tumors by therapeutic-ultrasound inhibits both tumor angiogenesis and growth

Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to prostate tumors in vivo. Sef is downregulated in vari...

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Detalles Bibliográficos
Autores principales: Mishel, Sabrin, Shneyer, Boris, Korsensky, Lina, Goldshmidt-Tran, Orit, Haber, Tom, Machluf, Marcelle, Ron, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678190/
https://www.ncbi.nlm.nih.gov/pubmed/29118380
http://dx.doi.org/10.1038/s41598-017-12408-1

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