Cargando…
Plasticity of hippocampal memories in humans
The human hippocampus is a brain region that supports episodic and spatial memory. Recent experiments have drawn on animal research and computational modelling to reveal how the unique computations and representations of the hippocampus support episodic and spatial memory. Invasive electrophysiologi...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Current Biology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678278/ https://www.ncbi.nlm.nih.gov/pubmed/28260633 http://dx.doi.org/10.1016/j.conb.2017.02.004 |
_version_ | 1783277409079918592 |
---|---|
author | Horner, Aidan J Doeller, Christian F |
author_facet | Horner, Aidan J Doeller, Christian F |
author_sort | Horner, Aidan J |
collection | PubMed |
description | The human hippocampus is a brain region that supports episodic and spatial memory. Recent experiments have drawn on animal research and computational modelling to reveal how the unique computations and representations of the hippocampus support episodic and spatial memory. Invasive electrophysiological recordings and non-invasive functional brain imaging have provided evidence for the rapid formation of hippocampal representations, as well as the ability of the hippocampus to both pattern-separate and pattern-complete input from the neocortex. Further, recent evidence has shown that hippocampal representations are in constant flux, undergoing a continual process of strengthening, weakening and altering. This research offers a glimpse into the highly plastic and flexible nature of the human hippocampal system in relation to episodic memory. |
format | Online Article Text |
id | pubmed-5678278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Current Biology |
record_format | MEDLINE/PubMed |
spelling | pubmed-56782782017-11-20 Plasticity of hippocampal memories in humans Horner, Aidan J Doeller, Christian F Curr Opin Neurobiol Article The human hippocampus is a brain region that supports episodic and spatial memory. Recent experiments have drawn on animal research and computational modelling to reveal how the unique computations and representations of the hippocampus support episodic and spatial memory. Invasive electrophysiological recordings and non-invasive functional brain imaging have provided evidence for the rapid formation of hippocampal representations, as well as the ability of the hippocampus to both pattern-separate and pattern-complete input from the neocortex. Further, recent evidence has shown that hippocampal representations are in constant flux, undergoing a continual process of strengthening, weakening and altering. This research offers a glimpse into the highly plastic and flexible nature of the human hippocampal system in relation to episodic memory. Current Biology 2017-04 /pmc/articles/PMC5678278/ /pubmed/28260633 http://dx.doi.org/10.1016/j.conb.2017.02.004 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Horner, Aidan J Doeller, Christian F Plasticity of hippocampal memories in humans |
title | Plasticity of hippocampal memories in humans |
title_full | Plasticity of hippocampal memories in humans |
title_fullStr | Plasticity of hippocampal memories in humans |
title_full_unstemmed | Plasticity of hippocampal memories in humans |
title_short | Plasticity of hippocampal memories in humans |
title_sort | plasticity of hippocampal memories in humans |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678278/ https://www.ncbi.nlm.nih.gov/pubmed/28260633 http://dx.doi.org/10.1016/j.conb.2017.02.004 |
work_keys_str_mv | AT horneraidanj plasticityofhippocampalmemoriesinhumans AT doellerchristianf plasticityofhippocampalmemoriesinhumans |