Smc3 Deacetylation by Hos1 Facilitates Efficient Dissolution of Sister Chromatid Cohesion during Early Anaphase

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Cohesins establish sister chromatid cohesion during S phase and are removed when cohesin Scc1 is cleaved by separase at anaphase onset. During this process, cohesin Smc3 undergoes a cycle of acetylation: Smc3 acetylation by Eco1 in S phase stabilizes cohesin association with chromosomes, and its dea...

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Detalles Bibliográficos
Autores principales: Li, Shuyu, Yue, Zuojun, Tanaka, Tomoyuki U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678280/
https://www.ncbi.nlm.nih.gov/pubmed/29100057
http://dx.doi.org/10.1016/j.molcel.2017.10.009

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