Lithium Intoxication: A Possible Interaction with Moxifloxacin

Lithium is a well-known treatment for patients with mood disorders. Intoxication by lithium may be lethal particularly in elderly due to altered pharmacokinetics, renal impairment or multiple drug use. We presented a 74-year-old female patient who had been stabile with lithium carbonate 600 mg/day f...

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Detalles Bibliográficos
Autores principales: Kayipmaz, Selvi, Altınöz, Ali Ercan, Ok, Nadide Elmas Gülcü
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678478/
https://www.ncbi.nlm.nih.gov/pubmed/29073753
http://dx.doi.org/10.9758/cpn.2017.15.4.407
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author Kayipmaz, Selvi
Altınöz, Ali Ercan
Ok, Nadide Elmas Gülcü
author_facet Kayipmaz, Selvi
Altınöz, Ali Ercan
Ok, Nadide Elmas Gülcü
author_sort Kayipmaz, Selvi
collection PubMed
description Lithium is a well-known treatment for patients with mood disorders. Intoxication by lithium may be lethal particularly in elderly due to altered pharmacokinetics, renal impairment or multiple drug use. We presented a 74-year-old female patient who had been stabile with lithium carbonate 600 mg/day for 5 years and developed lithium intoxication after bronchiolitis. She presented with altered mental status. The neurological signs resolved slowly after lithium and moxifloxacin were stopped immediately and fluid resuscitation administered. Considering possible drug interactions on elderly patients receiving lithium is essential.
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spelling pubmed-56784782017-11-15 Lithium Intoxication: A Possible Interaction with Moxifloxacin Kayipmaz, Selvi Altınöz, Ali Ercan Ok, Nadide Elmas Gülcü Clin Psychopharmacol Neurosci Case Report Lithium is a well-known treatment for patients with mood disorders. Intoxication by lithium may be lethal particularly in elderly due to altered pharmacokinetics, renal impairment or multiple drug use. We presented a 74-year-old female patient who had been stabile with lithium carbonate 600 mg/day for 5 years and developed lithium intoxication after bronchiolitis. She presented with altered mental status. The neurological signs resolved slowly after lithium and moxifloxacin were stopped immediately and fluid resuscitation administered. Considering possible drug interactions on elderly patients receiving lithium is essential. Korean College of Neuropsychopharmacology 2017-11 2017-11-30 /pmc/articles/PMC5678478/ /pubmed/29073753 http://dx.doi.org/10.9758/cpn.2017.15.4.407 Text en Copyright © 2017, Korean College of Neuropsychopharmacology This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kayipmaz, Selvi
Altınöz, Ali Ercan
Ok, Nadide Elmas Gülcü
Lithium Intoxication: A Possible Interaction with Moxifloxacin
title Lithium Intoxication: A Possible Interaction with Moxifloxacin
title_full Lithium Intoxication: A Possible Interaction with Moxifloxacin
title_fullStr Lithium Intoxication: A Possible Interaction with Moxifloxacin
title_full_unstemmed Lithium Intoxication: A Possible Interaction with Moxifloxacin
title_short Lithium Intoxication: A Possible Interaction with Moxifloxacin
title_sort lithium intoxication: a possible interaction with moxifloxacin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678478/
https://www.ncbi.nlm.nih.gov/pubmed/29073753
http://dx.doi.org/10.9758/cpn.2017.15.4.407
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AT oknadideelmasgulcu lithiumintoxicationapossibleinteractionwithmoxifloxacin

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