The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease–related pathology

INTRODUCTION: Alzheimer's disease (AD) and synucleinopathies share common pathological mechanisms. Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for AD, also increases the risk for dementia in pure synucleinopathies. We presently examined the effects of α-synuclein deficienc...

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Detalles Bibliográficos
Autores principales: Bar, Roni, Boehm-Cagan, Anat, Luz, Ishai, Kleper-Wall, Yarden, Michaelson, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678739/
https://www.ncbi.nlm.nih.gov/pubmed/29159264
http://dx.doi.org/10.1016/j.dadm.2017.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678739/
https://www.ncbi.nlm.nih.gov/pubmed/29159264
http://dx.doi.org/10.1016/j.dadm.2017.08.003

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