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The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease–related pathology
INTRODUCTION: Alzheimer's disease (AD) and synucleinopathies share common pathological mechanisms. Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for AD, also increases the risk for dementia in pure synucleinopathies. We presently examined the effects of α-synuclein deficienc...
Autores principales: | Bar, Roni, Boehm-Cagan, Anat, Luz, Ishai, Kleper-Wall, Yarden, Michaelson, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678739/ https://www.ncbi.nlm.nih.gov/pubmed/29159264 http://dx.doi.org/10.1016/j.dadm.2017.08.003 |
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