DHCR24 exerts neuroprotection upon inflammation-induced neuronal death

BACKGROUND: DHCR24, involved in the de novo synthesis of cholesterol and protection of neuronal cells against different stress conditions, has been shown to be selectively downregulated in neurons of the affected brain areas in Alzheimer’s disease. METHODS: Here, we investigated whether the overexpr...

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Detalles Bibliográficos
Autores principales: Martiskainen, Henna, Paldanius, Kaisa M. A., Natunen, Teemu, Takalo, Mari, Marttinen, Mikael, Leskelä, Stina, Huber, Nadine, Mäkinen, Petra, Bertling, Enni, Dhungana, Hiramani, Huuskonen, Mikko, Honkakoski, Paavo, Hotulainen, Pirta, Rilla, Kirsi, Koistinaho, Jari, Soininen, Hilkka, Malm, Tarja, Haapasalo, Annakaisa, Hiltunen, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678793/
https://www.ncbi.nlm.nih.gov/pubmed/29115990
http://dx.doi.org/10.1186/s12974-017-0991-6

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