Cargando…
Quantitative assessment of radiation dose and fractionation effects on normal tissue by utilizing a novel lung fibrosis index model
BACKGROUND: Normal lung tissue tolerance constitutes a limiting factor in delivering the required dose of radiotherapy to cure thoracic and chest wall malignancies. Radiation-induced lung fibrosis (RILF) is considered a critical determinant for late normal tissue complications. While RILF mouse mode...
Autores principales: | Zhou, Cheng, Jones, Bleddyn, Moustafa, Mahmoud, Schwager, Christian, Bauer, Julia, Yang, Bing, Cao, Liji, Jia, Min, Mairani, Andrea, Chen, Ming, Chen, Longhua, Debus, Juergen, Abdollahi, Amir |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678815/ https://www.ncbi.nlm.nih.gov/pubmed/29116014 http://dx.doi.org/10.1186/s13014-017-0912-y |
Ejemplares similares
-
Determining RBE for development of lung fibrosis induced by fractionated irradiation with carbon ions utilizing fibrosis index and high-LET BED model
por: Zhou, Cheng, et al.
Publicado: (2018) -
Modeling and multiscale characterization of the quantitative imaging based fibrosis index reveals pathophysiological, transcriptome and proteomic correlates of lung fibrosis induced by fractionated irradiation
por: Zhou, Cheng, et al.
Publicado: (2019) -
Modeling the Effect of Hypoxia and DNA Repair Inhibition on Cell Survival after Photon Irradiation
por: Liew, Hans, et al.
Publicado: (2019) -
The Impact of Sub-Millisecond Damage Fixation Kinetics on the In Vitro Sparing Effect at Ultra-High Dose Rate in UNIVERSE
por: Liew, Hans, et al.
Publicado: (2022) -
Do We Preserve Tumor Control Probability (TCP) in FLASH Radiotherapy? A Model-Based Analysis
por: Liew, Hans, et al.
Publicado: (2023)