Human pancreatic islet-derived extracellular vesicles modulate insulin expression in 3D-differentiating iPSC clusters

It has been suggested that extracellular vesicles (EVs) can mediate crosstalk between hormones and metabolites within pancreatic tissue. However, the possible effect of pancreatic EVs on stem cell differentiation into pancreatic lineages remains unknown. Herein, human islet-derived EVs (h-Islet-EVs)...

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Detalles Bibliográficos
Autores principales: Ribeiro, Diana, Andersson, Eva-Marie, Heath, Nikki, Persson-kry, Anette, Collins, Richard, Hicks, Ryan, Dekker, Niek, Forslöw, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678888/
https://www.ncbi.nlm.nih.gov/pubmed/29117231
http://dx.doi.org/10.1371/journal.pone.0187665

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