The emergence of NS5B resistance associated substitution S282T after sofosbuvir‐based treatment

S282T in NS5B is the primary amino acid substitution associated with resistance to sofosbuvir (SOF) but has rarely been detected in patients treated with a SOF‐based regimen. Here, the emergence and fitness of the S282T substitution in virologic failure patients administered SOF‐based regimens acros...

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Detalles Bibliográficos
Autores principales: Gane, Edward J., Metivier, Sophie, Nahass, Ronald, Ryan, Michael, Stedman, Catherine A., Svarovskaia, Evguenia S., Mo, Hongmei, Doehle, Brian, Dvory‐Sobol, Hadas, Hedskog, Charlotte, Lin, Ming, Brainard, Diana M., Yang, Jenny C., McHutchison, John G., Sulkowski, Mark, Younes, Ziad, Lawitz, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678900/
https://www.ncbi.nlm.nih.gov/pubmed/29404477
http://dx.doi.org/10.1002/hep4.1060

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