The new‐generation pan‐peroxisome proliferator‐activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis

IVA337 is a pan‐peroxisome proliferator‐activated receptor (PPAR) agonist with moderate and well‐balanced activity on the three PPAR isoforms (α, γ, δ). PPARs are regulators of lipid metabolism, inflammation, insulin resistance, and fibrogenesis. Different single or dual PPAR agonists have been inve...

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Detalles Bibliográficos
Autores principales: Wettstein, Guillaume, Luccarini, Jean‐Michel, Poekes, Laurence, Faye, Patrick, Kupkowski, Francine, Adarbes, Vanessa, Defrêne, Evelyne, Estivalet, Céline, Gawronski, Xavier, Jantzen, Ingrid, Philippot, Alain, Tessier, Julien, Tuyaa‐Boustugue, Pascale, Oakley, Fiona, Mann, Derek A., Leclercq, Isabelle, Francque, Sven, Konstantinova, Irena, Broqua, Pierre, Junien, Jean‐Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678909/
https://www.ncbi.nlm.nih.gov/pubmed/29404476
http://dx.doi.org/10.1002/hep4.1057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678909/
https://www.ncbi.nlm.nih.gov/pubmed/29404476
http://dx.doi.org/10.1002/hep4.1057

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