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A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis
The etiology of sporadic human chronic inflammatory diseases remains mostly unknown. To fill this gap, we developed a strategy that simultaneously integrates blood leukocyte responses to innate stimuli at the transcriptional, cellular, and secreted protein levels. When applied to systemic juvenile i...
Autores principales: | Cepika, Alma-Martina, Banchereau, Romain, Segura, Elodie, Ohouo, Marina, Cantarel, Brandi, Goller, Kristina, Cantrell, Victoria, Ruchaud, Emily, Gatewood, Elizabeth, Nguyen, Phuong, Gu, Jinghua, Anguiano, Esperanza, Zurawski, Sandra, Baisch, Jeanine M., Punaro, Marilynn, Baldwin, Nicole, Obermoser, Gerlinde, Palucka, Karolina, Banchereau, Jacques, Amigorena, Sebastian, Pascual, Virginia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679164/ https://www.ncbi.nlm.nih.gov/pubmed/28935693 http://dx.doi.org/10.1084/jem.20170412 |
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