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Redefining thymus medulla specialization for central tolerance
During αβT cell development, the thymus medulla represents an essential microenvironment for T cell tolerance. This functional specialization is attributed to its typical organized topology consisting of a branching structure that contains medullary thymic epithelial cell (mTEC) networks to support...
Autores principales: | Cosway, Emilie J., Lucas, Beth, James, Kieran D., Parnell, Sonia M., Carvalho-Gaspar, Manuela, White, Andrea J., Tumanov, Alexei V., Jenkinson, William E., Anderson, Graham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679166/ https://www.ncbi.nlm.nih.gov/pubmed/28830910 http://dx.doi.org/10.1084/jem.20171000 |
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