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Alzheimer’s disease: A matter of blood–brain barrier dysfunction?

The blood–brain barrier (BBB) keeps neurotoxic plasma-derived components, cells, and pathogens out of the brain. An early BBB breakdown and/or dysfunction have been shown in Alzheimer’s disease (AD) before dementia, neurodegeneration and/or brain atrophy occur. However, the role of BBB breakdown in...

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Detalles Bibliográficos
Autores principales:	Montagne, Axel, Zhao, Zhen, Zlokovic, Berislav V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679168/ https://www.ncbi.nlm.nih.gov/pubmed/29061693 http://dx.doi.org/10.1084/jem.20171406

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