Cargando…
ICAMs support B cell interactions with T follicular helper cells and promote clonal selection
The germinal center (GC) reaction begins with a diverse and expanded group of B cell clones bearing a wide range of antibody affinities. During GC colonization, B cells engage in long-lasting interactions with T follicular helper (Tfh) cells, a process that depends on antigen uptake and antigen pres...
Autores principales: | Zaretsky, Irina, Atrakchi, Ofir, Mazor, Roei D., Stoler-Barak, Liat, Biram, Adi, Feigelson, Sara W., Gitlin, Alexander D., Engelhardt, Britta, Shulman, Ziv |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679169/ https://www.ncbi.nlm.nih.gov/pubmed/28939548 http://dx.doi.org/10.1084/jem.20171129 |
Ejemplares similares
-
Stable contacts of naïve CD4 T cells with migratory dendritic cells are ICAM-1-dependent but dispensable for proliferation in vivo
por: Kozlovski, Stav, et al.
Publicado: (2019) -
Syk degradation restrains plasma cell formation and promotes zonal transitions in germinal centers
por: Davidzohn, Natalia, et al.
Publicado: (2019) -
B cell dissemination patterns during the germinal center reaction revealed by whole-organ imaging
por: Stoler-Barak, Liat, et al.
Publicado: (2019) -
Clonal composition and persistence of antigen‐specific circulating T follicular helper cells
por: Hu, Mengyun, et al.
Publicado: (2022) -
B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer’s Patches
por: Biram, Adi, et al.
Publicado: (2020)