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Spatially restricted JAG1-Notch signaling in human thymus provides suitable DC developmental niches

A key unsolved question regarding the developmental origin of conventional and plasmacytoid dendritic cells (cDCs and pDCs, respectively) resident in the steady-state thymus is whether early thymic progenitors (ETPs) could escape T cell fate constraints imposed normally by a Notch-inductive microenv...

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Detalles Bibliográficos
Autores principales:	Martín-Gayo, Enrique, González-García, Sara, García-León, María J., Murcia-Ceballos, Alba, Alcain, Juan, García-Peydró, Marina, Allende, Luis, de Andrés, Belén, Gaspar, María L., Toribio, María L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679173/ https://www.ncbi.nlm.nih.gov/pubmed/28947612 http://dx.doi.org/10.1084/jem.20161564

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