The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes

Myocardial infarction (MI) elicits massive inflammatory leukocyte recruitment to the heart. Here, we hypothesized that excessive leukocyte invasion leads to heart failure and death during acute myocardial ischemia. We found that shortly and transiently after onset of ischemia, human and mouse cardia...

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Detalles Bibliográficos
Autores principales: Anzai, Atsushi, Choi, Jennifer L., He, Shun, Fenn, Ashley M., Nairz, Manfred, Rattik, Sara, McAlpine, Cameron S., Mindur, John E., Chan, Christopher T., Iwamoto, Yoshiko, Tricot, Benoit, Wojtkiewicz, Gregory R., Weissleder, Ralph, Libby, Peter, Nahrendorf, Matthias, Stone, James R., Becher, Burkhard, Swirski, Filip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679174/
https://www.ncbi.nlm.nih.gov/pubmed/28978634
http://dx.doi.org/10.1084/jem.20170689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679174/
https://www.ncbi.nlm.nih.gov/pubmed/28978634
http://dx.doi.org/10.1084/jem.20170689

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