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The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes

Myocardial infarction (MI) elicits massive inflammatory leukocyte recruitment to the heart. Here, we hypothesized that excessive leukocyte invasion leads to heart failure and death during acute myocardial ischemia. We found that shortly and transiently after onset of ischemia, human and mouse cardia...

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Detalles Bibliográficos
Autores principales: Anzai, Atsushi, Choi, Jennifer L., He, Shun, Fenn, Ashley M., Nairz, Manfred, Rattik, Sara, McAlpine, Cameron S., Mindur, John E., Chan, Christopher T., Iwamoto, Yoshiko, Tricot, Benoit, Wojtkiewicz, Gregory R., Weissleder, Ralph, Libby, Peter, Nahrendorf, Matthias, Stone, James R., Becher, Burkhard, Swirski, Filip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679174/
https://www.ncbi.nlm.nih.gov/pubmed/28978634
http://dx.doi.org/10.1084/jem.20170689

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