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Inhibition of 5-lipoxygenase alleviates graft-versus-host disease

Leukotriene B(4) (LTB(4)), a proinflammatory mediator produced by the enzyme 5-lipoxygenase (5-LO), is associated with the development of many inflammatory diseases. In this study, we evaluated the participation of the 5-LO/LTB(4) axis in graft-versus-host disease (GVHD) pathogenesis by transplantin...

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Detalles Bibliográficos
Autores principales:	Rezende, Barbara Maximino, Athayde, Rayssa Maciel, Gonçalves, William Antônio, Resende, Carolina Braga, Teles de Tolêdo Bernardes, Priscila, Perez, Denise Alves, Esper, Lísia, Reis, Alesandra Côrte, Rachid, Milene Alvarenga, Castor, Marina Gomes Miranda e, Cunha, Thiago Mattar, Machado, Fabiana Simão, Teixeira, Mauro Martins, Pinho, Vanessa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679175/ https://www.ncbi.nlm.nih.gov/pubmed/28947611 http://dx.doi.org/10.1084/jem.20170261

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