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p21(−/−) mice exhibit enhanced bone regeneration after injury
BACKGROUND: p21((WAF1/CIP1/SDI1)), a cyclin dependent kinase inhibitor has been shown to influence cell proliferation, differentiation and apoptosis; but more recently, p21 has been implicated in tissue repair. Studies on p21((−/−)) knockout mice have demonstrated results that vary from complete reg...
Autores principales: | Premnath, Priyatha, Jorgenson, Britta, Hess, Ricarda, Tailor, Pankaj, Louie, Dante, Taiani, Jaymi, Boyd, Steven, Krawetz, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679350/ https://www.ncbi.nlm.nih.gov/pubmed/29121899 http://dx.doi.org/10.1186/s12891-017-1790-z |
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