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Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer
BACKGROUND: Pancreatic cancer, one of the top two most fatal cancers, is characterized by a desmoplastic reaction that creates a dense microenvironment, promoting hypoxia and inducing the epithelial-to-mesenchymal transition (EMT) to facilitate invasion and metastasis. Recent evidence indicates that...
Autores principales: | Li, Hongzhe, Wang, Xinjing, Wen, Chenlei, Huo, Zhen, Wang, Weishen, Zhan, Qian, Cheng, Dongfeng, Chen, Hao, Deng, Xiaxing, Peng, Chenghong, Shen, Baiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679488/ https://www.ncbi.nlm.nih.gov/pubmed/29121972 http://dx.doi.org/10.1186/s12943-017-0738-0 |
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