Haplotype CGC from XPD, hOGG1 and ITGA2 polymorphisms increases the risk of nasopharyngeal carcinoma in Malaysia

BACKGROUND: 8-oxoG, a common DNA lesion resulting from reactive oxygen species (ROS), has been shown to be associated with cancer initiation. hOGG1 DNA glycosylase is the primary enzyme responsible for excision of 8-oxoG through base excision repair (BER). Integrins are members of a family of cell s...

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Detalles Bibliográficos
Autores principales: Ban, Eng-Zhuan, Lye, Munn-Sann, Chong, Pei Pei, Yap, Yoke-Yeow, Lim, Siew Ying Crystale, Abdul Rahman, Hejar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679532/
https://www.ncbi.nlm.nih.gov/pubmed/29121049
http://dx.doi.org/10.1371/journal.pone.0187200

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