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Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study

BACKGROUND: Despite the reduction in reported incidence of tuberculosis globally, the burden of pulmonary tuberculosis (PTB) remains high in low- and middle- income countries, including China. The current study aims to evaluate the distribution and trend of PTB incidence in Xinjiang, the region with...

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Autores principales: He, Xiangyan, Cao, Mingqin, Mahapatra, Tanmay, Du, Xiangpin, Mahapatra, Sanchita, Li, Qifeng, Feng, Lei, Tang, Songyuan, Zhao, Zhen, Liu, Jinbao, Tang, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679610/
https://www.ncbi.nlm.nih.gov/pubmed/29121654
http://dx.doi.org/10.1371/journal.pone.0187592
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author He, Xiangyan
Cao, Mingqin
Mahapatra, Tanmay
Du, Xiangpin
Mahapatra, Sanchita
Li, Qifeng
Feng, Lei
Tang, Songyuan
Zhao, Zhen
Liu, Jinbao
Tang, Weiming
author_facet He, Xiangyan
Cao, Mingqin
Mahapatra, Tanmay
Du, Xiangpin
Mahapatra, Sanchita
Li, Qifeng
Feng, Lei
Tang, Songyuan
Zhao, Zhen
Liu, Jinbao
Tang, Weiming
author_sort He, Xiangyan
collection PubMed
description BACKGROUND: Despite the reduction in reported incidence of tuberculosis globally, the burden of pulmonary tuberculosis (PTB) remains high in low- and middle- income countries, including China. The current study aims to evaluate the distribution and trend of PTB incidence in Xinjiang, the region with the highest PTB burden in China. METHODS: We identified all confirmed PTB case records reported to the Chinese TB Information Management System (TBIMS) between 2011 and 2015. We analyzed these records to measure the annual incidence of reported smear-positive PTB cases in Xinjiang and its trend over time. We also analyzed incidence by gender, residential area, and region. Spatial analysis was used to describe the inter-regional disparity of the disease burden during the study period. RESULTS: We identified 212,216 smear-positive PTB cases between 2011 and 2015. The reported incidence increased from 180.8 cases in 2011 to 195.8 cases in 2015 per 100,000 population. The southern region of Xinjiang had the highest disease burden (257.8/100,000 in 2011 and 312.7/100,000 in 2015). More than 60% cases occurred in persons >45 years, and 76% of cases lived in rural areas. CONCLUSION: To reach the goal of elimination and control of TB, more comprehensive STOP TB strategies should be implemented in Xinjiang. Residents in the southern region and rural areas of Xinjiang require particular attention.
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spelling pubmed-56796102017-11-18 Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study He, Xiangyan Cao, Mingqin Mahapatra, Tanmay Du, Xiangpin Mahapatra, Sanchita Li, Qifeng Feng, Lei Tang, Songyuan Zhao, Zhen Liu, Jinbao Tang, Weiming PLoS One Research Article BACKGROUND: Despite the reduction in reported incidence of tuberculosis globally, the burden of pulmonary tuberculosis (PTB) remains high in low- and middle- income countries, including China. The current study aims to evaluate the distribution and trend of PTB incidence in Xinjiang, the region with the highest PTB burden in China. METHODS: We identified all confirmed PTB case records reported to the Chinese TB Information Management System (TBIMS) between 2011 and 2015. We analyzed these records to measure the annual incidence of reported smear-positive PTB cases in Xinjiang and its trend over time. We also analyzed incidence by gender, residential area, and region. Spatial analysis was used to describe the inter-regional disparity of the disease burden during the study period. RESULTS: We identified 212,216 smear-positive PTB cases between 2011 and 2015. The reported incidence increased from 180.8 cases in 2011 to 195.8 cases in 2015 per 100,000 population. The southern region of Xinjiang had the highest disease burden (257.8/100,000 in 2011 and 312.7/100,000 in 2015). More than 60% cases occurred in persons >45 years, and 76% of cases lived in rural areas. CONCLUSION: To reach the goal of elimination and control of TB, more comprehensive STOP TB strategies should be implemented in Xinjiang. Residents in the southern region and rural areas of Xinjiang require particular attention. Public Library of Science 2017-11-09 /pmc/articles/PMC5679610/ /pubmed/29121654 http://dx.doi.org/10.1371/journal.pone.0187592 Text en © 2017 He et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
He, Xiangyan
Cao, Mingqin
Mahapatra, Tanmay
Du, Xiangpin
Mahapatra, Sanchita
Li, Qifeng
Feng, Lei
Tang, Songyuan
Zhao, Zhen
Liu, Jinbao
Tang, Weiming
Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study
title Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study
title_full Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study
title_fullStr Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study
title_full_unstemmed Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study
title_short Burden of tuberculosis in Xinjiang between 2011 and 2015: A surveillance data-based study
title_sort burden of tuberculosis in xinjiang between 2011 and 2015: a surveillance data-based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679610/
https://www.ncbi.nlm.nih.gov/pubmed/29121654
http://dx.doi.org/10.1371/journal.pone.0187592
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