Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease

BACKGROUND: There are no effective treatments or validated clinical response markers in systemic sclerosis (SSc). We assessed imaging biomarkers and performed gene expression profiling in a single-arm open-label clinical trial of tyrosine kinase inhibitor dasatinib in patients with SSc-associated in...

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Detalles Bibliográficos
Autores principales: Martyanov, Viktor, Kim, Grace-Hyun J., Hayes, Wendy, Du, Shuyan, Ganguly, Bishu J., Sy, Oumar, Lee, Sun Ku, Bogatkevich, Galina S., Schieven, Gary L., Schiopu, Elena, Marangoni, Roberta Gonçalves, Goldin, Jonathan, Whitfield, Michael L., Varga, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679625/
https://www.ncbi.nlm.nih.gov/pubmed/29121645
http://dx.doi.org/10.1371/journal.pone.0187580

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