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Broadening the functionality of a J-protein/Hsp70 molecular chaperone system

By binding to a multitude of polypeptide substrates, Hsp70-based molecular chaperone systems perform a range of cellular functions. All J-protein co-chaperones play the essential role, via action of their J-domains, of stimulating the ATPase activity of Hsp70, thereby stabilizing its interaction wit...

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Detalles Bibliográficos
Autores principales: Schilke, Brenda A., Ciesielski, Szymon J., Ziegelhoffer, Thomas, Kamiya, Erina, Tonelli, Marco, Lee, Woonghee, Cornilescu, Gabriel, Hines, Justin K., Markley, John L., Craig, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679652/
https://www.ncbi.nlm.nih.gov/pubmed/29084221
http://dx.doi.org/10.1371/journal.pgen.1007084