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Broadening the functionality of a J-protein/Hsp70 molecular chaperone system
By binding to a multitude of polypeptide substrates, Hsp70-based molecular chaperone systems perform a range of cellular functions. All J-protein co-chaperones play the essential role, via action of their J-domains, of stimulating the ATPase activity of Hsp70, thereby stabilizing its interaction wit...
Autores principales: | Schilke, Brenda A., Ciesielski, Szymon J., Ziegelhoffer, Thomas, Kamiya, Erina, Tonelli, Marco, Lee, Woonghee, Cornilescu, Gabriel, Hines, Justin K., Markley, John L., Craig, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679652/ https://www.ncbi.nlm.nih.gov/pubmed/29084221 http://dx.doi.org/10.1371/journal.pgen.1007084 |
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