Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense

The activation of interferon (IFN)-regulatory factor-3 (IRF3), characterized by phosphorylation and nuclear translocation of the latent transcription factor, is central to initiating innate antiviral responses. Whereas much has been learned about the upstream pathways and signaling mechanisms leadin...

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Detalles Bibliográficos
Autores principales: Kumthip, Kattareeya, Yang, Darong, Li, Nan L., Zhang, Yunzhi, Fan, Meiyun, Sethuraman, Aarti, Li, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679654/
https://www.ncbi.nlm.nih.gov/pubmed/29084253
http://dx.doi.org/10.1371/journal.ppat.1006713

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