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Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin

Niemann-Pick Protein C2 (npc2) is a small soluble protein critical for cholesterol transport within and from the lysosome and the late endosome. Intriguingly, npc2-mediated cholesterol transport has been shown to be modulated by lipids, yet the molecular mechanism of npc2-membrane interactions has r...

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Detalles Bibliográficos
Autores principales:	Enkavi, Giray, Mikkolainen, Heikki, Güngör, Burçin, Ikonen, Elina, Vattulainen, Ilpo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679659/ https://www.ncbi.nlm.nih.gov/pubmed/29084218 http://dx.doi.org/10.1371/journal.pcbi.1005831

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