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Different molecular complexes that mediate transcriptional induction and repression by FoxP3
FoxP3 conditions the transcriptional signature and functional facets of regulatory T (T(reg)) cells. Its mechanism of action, whether as an activator or a repressor, remains unclear. Chromatin analysis shows that FoxP3 binds active enhancer elements, not repressed chromatin, around loci over- and un...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679728/ https://www.ncbi.nlm.nih.gov/pubmed/28892470 http://dx.doi.org/10.1038/ni.3835 |