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Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid

Paraneoplastic hepatopathy has been reported with various malignancies, most commonly with renal cell cancer. This non-metastatic hepatic dysfunction in such malignancies is known as Stauffer syndrome. We describe a 61-year-old man who presented with symptoms of bowel obstruction with marked cholest...

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Autores principales: Mehta, Dhruv, Chugh, Priyanka, Chawla, Lavneet, Jodorkovsky, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679777/
https://www.ncbi.nlm.nih.gov/pubmed/29138755
http://dx.doi.org/10.14309/crj.2017.117
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author Mehta, Dhruv
Chugh, Priyanka
Chawla, Lavneet
Jodorkovsky, Daniela
author_facet Mehta, Dhruv
Chugh, Priyanka
Chawla, Lavneet
Jodorkovsky, Daniela
author_sort Mehta, Dhruv
collection PubMed
description Paraneoplastic hepatopathy has been reported with various malignancies, most commonly with renal cell cancer. This non-metastatic hepatic dysfunction in such malignancies is known as Stauffer syndrome. We describe a 61-year-old man who presented with symptoms of bowel obstruction with marked cholestasis and high levels of alkaline phosphatase and bilirubin. Imaging revealed an unremarkable liver and a mass in the ileocecal valve with mesenteric lymphadenopathy. Biopsies were consistent with a carcinoid tumor. Liver dysfunction gradually resolved after surgical resection of the tumor. Paraneoplastic syndrome should be considered in the differential diagnosis for patients with carcinoid tumors who present with cholestasis.
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spelling pubmed-56797772017-11-14 Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid Mehta, Dhruv Chugh, Priyanka Chawla, Lavneet Jodorkovsky, Daniela ACG Case Rep J Case Report Paraneoplastic hepatopathy has been reported with various malignancies, most commonly with renal cell cancer. This non-metastatic hepatic dysfunction in such malignancies is known as Stauffer syndrome. We describe a 61-year-old man who presented with symptoms of bowel obstruction with marked cholestasis and high levels of alkaline phosphatase and bilirubin. Imaging revealed an unremarkable liver and a mass in the ileocecal valve with mesenteric lymphadenopathy. Biopsies were consistent with a carcinoid tumor. Liver dysfunction gradually resolved after surgical resection of the tumor. Paraneoplastic syndrome should be considered in the differential diagnosis for patients with carcinoid tumors who present with cholestasis. American College of Gastroenterology 2017-11-08 /pmc/articles/PMC5679777/ /pubmed/29138755 http://dx.doi.org/10.14309/crj.2017.117 Text en Copyright © Mehta et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Mehta, Dhruv
Chugh, Priyanka
Chawla, Lavneet
Jodorkovsky, Daniela
Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid
title Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid
title_full Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid
title_fullStr Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid
title_full_unstemmed Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid
title_short Paraneoplastic Hepatopathy Associated with Gastrointestinal Carcinoid
title_sort paraneoplastic hepatopathy associated with gastrointestinal carcinoid
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679777/
https://www.ncbi.nlm.nih.gov/pubmed/29138755
http://dx.doi.org/10.14309/crj.2017.117
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