Organocatalytic enantio- and diastereoselective cycloetherification via dynamic kinetic resolution of chiral cyanohydrins

Enantioselective approaches to synthesize six-membered oxacycles with multiple stereogenic centres are in high demand to enable the discovery of new therapeutic agents. Here we present a concise organocatalytic cycloetherification for the highly enantio- and diastereoselective synthesis of tetrahydr...

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Detalles Bibliográficos
Autores principales: Yoneda, Naoki, Fujii, Yuki, Matsumoto, Akira, Asano, Keisuke, Matsubara, Seijiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680189/
https://www.ncbi.nlm.nih.gov/pubmed/29123080
http://dx.doi.org/10.1038/s41467-017-01099-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680189/
https://www.ncbi.nlm.nih.gov/pubmed/29123080
http://dx.doi.org/10.1038/s41467-017-01099-x

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