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Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4

Atropine is a clinically relevant anticholinergic drug, which blocks inhibitory effects of the parasympathetic neurotransmitter acetylcholine on heart rate leading to tachycardia. However, many cardiac effects of atropine cannot be adequately explained solely by its antagonism at muscarinic receptor...

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Detalles Bibliográficos
Autores principales:	Perera, Ruwan K., Fischer, Thomas H., Wagner, Michael, Dewenter, Matthias, Vettel, Christiane, Bork, Nadja I., Maier, Lars S., Conti, Marco, Wess, Juergen, El-Armouche, Ali, Hasenfuß, Gerd, Nikolaev, Viacheslav O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680190/ https://www.ncbi.nlm.nih.gov/pubmed/29123207 http://dx.doi.org/10.1038/s41598-017-15632-x

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