Induction of glucose uptake in skeletal muscle by central leptin is mediated by muscle β(2)-adrenergic receptor but not by AMPK

Leptin increases glucose uptake and fatty acid oxidation (FAO) in red-type skeletal muscle. However, the mechanism remains unknown. We have investigated the role of β(2)-adrenergic receptor (AR), the major β-AR isoform in skeletal muscle, and AMPK in leptin-induced muscle glucose uptake of mice. Lep...

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Detalles Bibliográficos
Autores principales: Shiuchi, Tetsuya, Toda, Chitoku, Okamoto, Shiki, Coutinho, Eulalia A., Saito, Kumiko, Miura, Shinji, Ezaki, Osamu, Minokoshi, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680211/
https://www.ncbi.nlm.nih.gov/pubmed/29123236
http://dx.doi.org/10.1038/s41598-017-15548-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680211/
https://www.ncbi.nlm.nih.gov/pubmed/29123236
http://dx.doi.org/10.1038/s41598-017-15548-6

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