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Induction of glucose uptake in skeletal muscle by central leptin is mediated by muscle β(2)-adrenergic receptor but not by AMPK
Leptin increases glucose uptake and fatty acid oxidation (FAO) in red-type skeletal muscle. However, the mechanism remains unknown. We have investigated the role of β(2)-adrenergic receptor (AR), the major β-AR isoform in skeletal muscle, and AMPK in leptin-induced muscle glucose uptake of mice. Lep...
Autores principales: | Shiuchi, Tetsuya, Toda, Chitoku, Okamoto, Shiki, Coutinho, Eulalia A., Saito, Kumiko, Miura, Shinji, Ezaki, Osamu, Minokoshi, Yasuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680211/ https://www.ncbi.nlm.nih.gov/pubmed/29123236 http://dx.doi.org/10.1038/s41598-017-15548-6 |
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