Differential T Cell Signaling Pathway Activation by Tacrolimus and Belatacept after Kidney Transplantation: Post Hoc Analysis of a Randomised-Controlled Trial

Pharmacokinetic immunosuppressive drug monitoring poorly correlates with clinical outcomes after solid organ transplantation. A promising method for pharmacodynamic monitoring of tacrolimus (TAC) in T cell subsets of transplant recipients might be the measurement of (phosphorylated) p38MAPK, ERK1/2...

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Detalles Bibliográficos
Autores principales: Kannegieter, Nynke M., Hesselink, Dennis A., Dieterich, Marjolein, de Graav, Gretchen N., Kraaijeveld, Rens, Baan, Carla C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680251/
https://www.ncbi.nlm.nih.gov/pubmed/29123208
http://dx.doi.org/10.1038/s41598-017-15542-y

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