Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes

Despite impressive clinical success, cancer immunotherapy based on immune checkpoint blockade remains ineffective in many patients due to tumoral resistance. Here we use the autochthonous TiRP melanoma model, which recapitulates the tumoral resistance signature observed in human melanomas. TiRP tumo...

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Detalles Bibliográficos
Autores principales: Zhu, Jingjing, Powis de Tenbossche, Céline G., Cané, Stefania, Colau, Didier, van Baren, Nicolas, Lurquin, Christophe, Schmitt-Verhulst, Anne-Marie, Liljeström, Peter, Uyttenhove, Catherine, Van den Eynde, Benoit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680273/
https://www.ncbi.nlm.nih.gov/pubmed/29123081
http://dx.doi.org/10.1038/s41467-017-00784-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680273/
https://www.ncbi.nlm.nih.gov/pubmed/29123081
http://dx.doi.org/10.1038/s41467-017-00784-1

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