Cargando…

Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes

Despite impressive clinical success, cancer immunotherapy based on immune checkpoint blockade remains ineffective in many patients due to tumoral resistance. Here we use the autochthonous TiRP melanoma model, which recapitulates the tumoral resistance signature observed in human melanomas. TiRP tumo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Jingjing, Powis de Tenbossche, Céline G., Cané, Stefania, Colau, Didier, van Baren, Nicolas, Lurquin, Christophe, Schmitt-Verhulst, Anne-Marie, Liljeström, Peter, Uyttenhove, Catherine, Van den Eynde, Benoit J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680273/ https://www.ncbi.nlm.nih.gov/pubmed/29123081 http://dx.doi.org/10.1038/s41467-017-00784-1

Ejemplares similares

Epithelial-Mesenchymal-Transition-Like and TGFβ Pathways Associated with Autochthonous Inflammatory Melanoma Development in Mice
por: Wehbe, Maria, et al.
Publicado: (2012)

TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism
por: Canè, Stefania, et al.
Publicado: (2021)

Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
por: Finisguerra, Veronica, et al.
Publicado: (2023)

Tryptophan-Degrading Enzymes in Tumoral Immune Resistance
por: van Baren, Nicolas, et al.
Publicado: (2015)

Expression profile of the human IDO1 protein, a cancer drug target involved in tumoral immune resistance
por: Vigneron, Nathalie, et al.
Publicado: (2015)

The Production of a New MAGE-3 Peptide Presented to Cytolytic T Lymphocytes by HLA-B40 Requires the Immunoproteasome
por: Schultz, Erwin S., et al.
Publicado: (2002)

Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma
por: Lopes, Alessandra, et al.
Publicado: (2018)

Tumor-infiltrating lymphocytes for melanoma immunotherapy
por: Kepp, Oliver, et al.
Publicado: (2023)

microRNA-155, Induced by Interleukin-1ß, Represses the Expression of Microphthalmia-Associated Transcription Factor (MITF-M) in Melanoma Cells
por: Arts, Nathalie, et al.
Publicado: (2015)

Contrasting frequencies of antitumor and anti-vaccine T cells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen
por: Lurquin, Christophe, et al.
Publicado: (2005)

384 Jessner-kanoff Lymphocytic Infiltrate as a Side Effect of Immunotherapy
por: Yalcin, Arzu Didem, et al.
Publicado: (2012)

Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
por: Wimmers, Florian, et al.
Publicado: (2014)

Tumor-Infiltrating Lymphocytes in Colorectal Cancer: The Fundamental Indication and Application on Immunotherapy
por: Bai, Ziyi, et al.
Publicado: (2022)

An Alternative Open Reading Frame of the Human Macrophage Colony-Stimulating Factor Gene Is Independently Translated and Codes for an Antigenic Peptide of 14 Amino Acids Recognized by Tumor-Infiltrating Cd8 T Lymphocytes
por: Probst-Kepper, Michael, et al.
Publicado: (2001)

Extent and location of tumor infiltrating lymphocytes in microsatellite stable colon cancer predict outcome to adjuvant active specific immunotherapy
por: Turksma, Annelies, et al.
Publicado: (2015)

Immunotherapy with immune checkpoint inhibitors in colorectal cancer: what is the future beyond deficient mismatch-repair tumours?
por: Huyghe, Nicolas, et al.
Publicado: (2019)

The emergence of tumor-infiltrating lymphocytes in nasopharyngeal carcinoma: Predictive value and immunotherapy implications
por: Yang, Liu, et al.
Publicado: (2021)

Biomarkers of Response and Resistance to Immunotherapy in Microsatellite Stable Colorectal Cancer: Toward a New Personalized Medicine
por: Huyghe, Nicolas, et al.
Publicado: (2022)

Disrupted Lymph Node and Splenic Stroma in Mice with Induced Inflammatory Melanomas Is Associated with Impaired Recruitment of T and Dendritic Cells
por: Soudja, Saïdi M., et al.
Publicado: (2011)

Tumor-infiltrating lymphocyte: features and prognosis of lymphocytes infiltration on colorectal cancer
por: Qin, Miao, et al.
Publicado: (2023)

Proteasome Subtypes and Regulators in the Processing of Antigenic Peptides Presented by Class I Molecules of the Major Histocompatibility Complex
por: Vigneron, Nathalie, et al.
Publicado: (2014)

Ex vivo expansion of tumor-infiltrating lymphocytes from nasopharyngeal carcinoma patients for adoptive immunotherapy
por: He, Jia, et al.
Publicado: (2012)

iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer
por: Ding, Naiqing, et al.
Publicado: (2019)

A New Antigen Recognized by Cytolytic T Lymphocytes on a Human Kidney Tumor Results from Reverse Strand Transcription
por: Van den Eynde, Benoît J., et al.
Publicado: (1999)

Targeting tumour-reprogrammed myeloid cells: the new battleground in cancer immunotherapy
por: De Sanctis, Francesco, et al.
Publicado: (2022)

Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer: A Proposal for Combining Immunohistochemistry and Gene Expression Analysis to Refine Scoring
por: Locy, Hanne, et al.
Publicado: (2022)

Adoptive transfer of tumor-infiltrating lymphocytes in melanoma: a viable treatment option
por: Rohaan, Maartje W., et al.
Publicado: (2018)

FOXP1 negatively regulates tumor infiltrating lymphocyte migration in human breast cancer
por: De Silva, Pushpamali, et al.
Publicado: (2018)

Mixed lymphocyte reactivity and cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes in C57BL/10 congenic and B10.A recombinant mouse strains
por: Shearer, GM, et al.
Publicado: (1975)

Phase I study of adjuvant immunotherapy with autologous tumor-infiltrating lymphocytes in locally advanced cervical cancer
por: Huang, He, et al.
Publicado: (2022)

Diffuse Pigment Release in a Patient Undergoing Tumor-Infiltrating Lymphocyte Immunotherapy for Acral Malignant Melanoma
por: Kerley, Madison, et al.
Publicado: (2023)

Lack of myeloid cell infiltration as an acquired resistance strategy to immunotherapy
por: Beyranvand Nejad, Elham, et al.
Publicado: (2020)

Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pleomorphic Lobular Breast Carcinoma
por: Göker, Menekse, et al.
Publicado: (2023)

Characteristics of the Immune Cell Infiltration Landscape in Gastric Cancer to Assistant Immunotherapy
por: Li, Chenlu, et al.
Publicado: (2022)

Editorial: Heme proteins: key players in the regulation of immune responses
por: Volpi, Claudia, et al.
Publicado: (2023)

The Significance of Lymphocytic Infiltration in Neuroblastoma
por: Lauder, I., et al.
Publicado: (1972)

A construction heuristic for the capacitated Steiner tree problem
por: Van den Eynde, Simon, et al.
Publicado: (2022)

Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy
por: Verdeil, Grégory, et al.
Publicado: (2019)

A Fast Interlock Detection System for High-Power Switch Protection
por: Van Trappen, Pieter, et al.
Publicado: (2015)

Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes
por: Solvay, Marie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c9p5j9h9nno9pq01eieof3q1q1