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Phospholipid flippase ATP11C is endocytosed and downregulated following Ca(2+)-mediated protein kinase C activation
We and others showed that ATP11A and ATP11C, members of the P4-ATPase family, translocate phosphatidylserine (PS) and phosphatidylethanolamine from the exoplasmic to the cytoplasmic leaflets at the plasma membrane. PS exposure on the outer leaflet of the plasma membrane in activated platelets, eryth...
Autores principales: | Takatsu, Hiroyuki, Takayama, Masahiro, Naito, Tomoki, Takada, Naoto, Tsumagari, Kazuya, Ishihama, Yasushi, Nakayama, Kazuhisa, Shin, Hye-Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680300/ https://www.ncbi.nlm.nih.gov/pubmed/29123098 http://dx.doi.org/10.1038/s41467-017-01338-1 |
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