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Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty

PURPOSE: Local infiltration analgesia (LIA) is commonly used for postoperative pain management following total hip arthroplasty (THA). However, the long-term effects of the component drugs are unclear. The aim of our study was to investigate functional outcome, quality of life, chronic post-surgical...

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Autores principales: Kuchálik, Ján, Magnuson, Anders, Lundin, Anders, Gupta, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680378/
https://www.ncbi.nlm.nih.gov/pubmed/28856511
http://dx.doi.org/10.1007/s00540-017-2403-6
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author Kuchálik, Ján
Magnuson, Anders
Lundin, Anders
Gupta, Anil
author_facet Kuchálik, Ján
Magnuson, Anders
Lundin, Anders
Gupta, Anil
author_sort Kuchálik, Ján
collection PubMed
description PURPOSE: Local infiltration analgesia (LIA) is commonly used for postoperative pain management following total hip arthroplasty (THA). However, the long-term effects of the component drugs are unclear. The aim of our study was to investigate functional outcome, quality of life, chronic post-surgical pain, and adverse events in patients within 2 years of undergoing THA. METHODS: The study was a secondary analysis of data from a previous larger study. Eighty patients were randomized to receive either intrathecal morphine (Group ITM) or local infiltration analgesia (Group LIA) for pain management in a double-blind study. The parameters measured were patient-assessed functional outcome [using the Hip dysfunction and Osteo-arthritis Outcome Score (HOOS) questionnaire], health-related quality of life [using the European Quality of Life–5 dimensions (EQ-5D) questionnaire and the 36-Item Short Form Health Survey (SF-36) score], and pain using the numeric rating score (NRS), with persistent post-surgical pain having a NRS of > 3 or a HOOS pain sub-score of > 30. All complications and adverse events were investigated during the first 2 years after primary surgery. RESULTS: Pain intensity and rescue analgesic consumption were similar between the groups after hospital discharge. No differences were found in HOOS or SF-36 score between the groups up to 6 months after surgery. A significant group × time interaction was seen in the EQ 5D form in favor of the LIA group. No between-group difference in persistent post-surgical pain was found at 3 or 6 months, or in adverse events up to 2 years after surgery. CONCLUSION: Analysis of functional outcome, quality of life, and post-discharge surgical pain did not reveal significant differences between patients receiving LIA and those receiving ITM. LIA was found to be a safe technique for THA during the long-term follow-up. However, it should be noted that these conclusions are based on a limited number of patients.
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spelling pubmed-56803782017-11-21 Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty Kuchálik, Ján Magnuson, Anders Lundin, Anders Gupta, Anil J Anesth Original Article PURPOSE: Local infiltration analgesia (LIA) is commonly used for postoperative pain management following total hip arthroplasty (THA). However, the long-term effects of the component drugs are unclear. The aim of our study was to investigate functional outcome, quality of life, chronic post-surgical pain, and adverse events in patients within 2 years of undergoing THA. METHODS: The study was a secondary analysis of data from a previous larger study. Eighty patients were randomized to receive either intrathecal morphine (Group ITM) or local infiltration analgesia (Group LIA) for pain management in a double-blind study. The parameters measured were patient-assessed functional outcome [using the Hip dysfunction and Osteo-arthritis Outcome Score (HOOS) questionnaire], health-related quality of life [using the European Quality of Life–5 dimensions (EQ-5D) questionnaire and the 36-Item Short Form Health Survey (SF-36) score], and pain using the numeric rating score (NRS), with persistent post-surgical pain having a NRS of > 3 or a HOOS pain sub-score of > 30. All complications and adverse events were investigated during the first 2 years after primary surgery. RESULTS: Pain intensity and rescue analgesic consumption were similar between the groups after hospital discharge. No differences were found in HOOS or SF-36 score between the groups up to 6 months after surgery. A significant group × time interaction was seen in the EQ 5D form in favor of the LIA group. No between-group difference in persistent post-surgical pain was found at 3 or 6 months, or in adverse events up to 2 years after surgery. CONCLUSION: Analysis of functional outcome, quality of life, and post-discharge surgical pain did not reveal significant differences between patients receiving LIA and those receiving ITM. LIA was found to be a safe technique for THA during the long-term follow-up. However, it should be noted that these conclusions are based on a limited number of patients. Springer Japan 2017-08-30 2017 /pmc/articles/PMC5680378/ /pubmed/28856511 http://dx.doi.org/10.1007/s00540-017-2403-6 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Kuchálik, Ján
Magnuson, Anders
Lundin, Anders
Gupta, Anil
Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
title Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
title_full Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
title_fullStr Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
title_full_unstemmed Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
title_short Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
title_sort local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680378/
https://www.ncbi.nlm.nih.gov/pubmed/28856511
http://dx.doi.org/10.1007/s00540-017-2403-6
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