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Camptothecin suppresses NRF2–ARE activity and sensitises hepatocellular carcinoma cells to anticancer drugs

BACKGROUND: Resistance to chemotherapy is a major obstacle in the treatment of human hepatocellular carcinoma (HCC). Despite playing an important role in chemoprevention, nuclear factor erythroid 2-related factor 2 (NRF2) also contributes to chemo- and radio-resistance. The current study focusses on...

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Detalles Bibliográficos
Autores principales:	Chen, Feng, Wang, Huihui, Zhu, Jiayu, Zhao, Rui, Xue, Peng, Zhang, Qiang, Bud Nelson, M, Qu, Weidong, Feng, Bo, Pi, Jingbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680465/ https://www.ncbi.nlm.nih.gov/pubmed/28910823 http://dx.doi.org/10.1038/bjc.2017.317

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