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Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention

AIM: To compare metabolic control and complications in people with type 2 diabetes in Nauru and the Solomon Islands before and after a project intervention. METHODS: This follow-up study compared metabolic control and complications in a cohort of 216 people with diabetes (81 from Nauru and 135 from...

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Autores principales: Win Tin, Si Thu, Laesango, Nevalyn, Gadabu, Eva, Colagiuri, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680475/
https://www.ncbi.nlm.nih.gov/pubmed/29159128
http://dx.doi.org/10.1016/j.jcte.2016.03.001
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author Win Tin, Si Thu
Laesango, Nevalyn
Gadabu, Eva
Colagiuri, Ruth
author_facet Win Tin, Si Thu
Laesango, Nevalyn
Gadabu, Eva
Colagiuri, Ruth
author_sort Win Tin, Si Thu
collection PubMed
description AIM: To compare metabolic control and complications in people with type 2 diabetes in Nauru and the Solomon Islands before and after a project intervention. METHODS: This follow-up study compared metabolic control and complications in a cohort of 216 people with diabetes (81 from Nauru and 135 from the Solomon Islands) at baseline and 15 months following a project intervention (upgrading and equipping the existing diabetes centres, and providing training and clinical support systems) aimed at improving the quality of clinical diabetes care. Subjects were screened using a standardised protocol which gathered information on demographics, treatment, physical and biochemical parameters and their outcomes. RESULTS: At follow-up, glycaemic control had improved and mean HbA1c had decreased in study participants in both Nauru (mean difference (MD) = −0.9 ± 2.3%) and the Solomon Islands (MD = −0.6 ± 1.4%), P < 0.001. Mean blood pressure was reduced in the Solomon Islands (systolic MD = −11.6 ± 19.2 mmHg and diastolic MD = −5.4 ± 10.5 mmHg), P < 0.001. There were no significant changes in mean blood lipids or albumin–creatinine ratio. Overall the percentage of subjects achieving recommended clinical targets increased. However these percentages remained low, e.g. 23.5% of participants in Nauru and 20.7% in the Solomon Islands achieved an HbA1c target <7% (53 mmol/mol). A trend towards lower complications rates of foot problems was observed but there were no significant changes in the prevalence of other diabetes complications. CONCLUSIONS: This study indicates improved metabolic control but little change in diabetes complications 15 months after intervention. Efforts to improve and evaluate the ongoing quality and accessibility of diabetes care in Pacific Island settings need to be further strengthened.
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spelling pubmed-56804752017-11-20 Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention Win Tin, Si Thu Laesango, Nevalyn Gadabu, Eva Colagiuri, Ruth J Clin Transl Endocrinol Research Paper AIM: To compare metabolic control and complications in people with type 2 diabetes in Nauru and the Solomon Islands before and after a project intervention. METHODS: This follow-up study compared metabolic control and complications in a cohort of 216 people with diabetes (81 from Nauru and 135 from the Solomon Islands) at baseline and 15 months following a project intervention (upgrading and equipping the existing diabetes centres, and providing training and clinical support systems) aimed at improving the quality of clinical diabetes care. Subjects were screened using a standardised protocol which gathered information on demographics, treatment, physical and biochemical parameters and their outcomes. RESULTS: At follow-up, glycaemic control had improved and mean HbA1c had decreased in study participants in both Nauru (mean difference (MD) = −0.9 ± 2.3%) and the Solomon Islands (MD = −0.6 ± 1.4%), P < 0.001. Mean blood pressure was reduced in the Solomon Islands (systolic MD = −11.6 ± 19.2 mmHg and diastolic MD = −5.4 ± 10.5 mmHg), P < 0.001. There were no significant changes in mean blood lipids or albumin–creatinine ratio. Overall the percentage of subjects achieving recommended clinical targets increased. However these percentages remained low, e.g. 23.5% of participants in Nauru and 20.7% in the Solomon Islands achieved an HbA1c target <7% (53 mmol/mol). A trend towards lower complications rates of foot problems was observed but there were no significant changes in the prevalence of other diabetes complications. CONCLUSIONS: This study indicates improved metabolic control but little change in diabetes complications 15 months after intervention. Efforts to improve and evaluate the ongoing quality and accessibility of diabetes care in Pacific Island settings need to be further strengthened. Elsevier 2016-03-23 /pmc/articles/PMC5680475/ /pubmed/29159128 http://dx.doi.org/10.1016/j.jcte.2016.03.001 Text en © 2016 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Paper
Win Tin, Si Thu
Laesango, Nevalyn
Gadabu, Eva
Colagiuri, Ruth
Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention
title Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention
title_full Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention
title_fullStr Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention
title_full_unstemmed Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention
title_short Comparing metabolic control and complications in type 2 diabetes in two Pacific Islands at baseline and following diabetes care intervention
title_sort comparing metabolic control and complications in type 2 diabetes in two pacific islands at baseline and following diabetes care intervention
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680475/
https://www.ncbi.nlm.nih.gov/pubmed/29159128
http://dx.doi.org/10.1016/j.jcte.2016.03.001
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