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Optimized purification strategies for the elimination of non-specific products in the isolation of GAD65-specific monoclonal autoantibodies

Autoantibodies against antigens expressed by insulin-producing β cells are circulating in both healthy individuals and patients at risk of developing Type 1 diabetes. Recent studies suggest that another set of antibodies (anti-idiotypic antibodies) exists in this antibody/antigen interacting network...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Macmillan, Henriette, Madec, Anne-Marie, Mellins, Elizabeth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680538/
https://www.ncbi.nlm.nih.gov/pubmed/29167731
http://dx.doi.org/10.12688/f1000research.6467.2