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Optimized purification strategies for the elimination of non-specific products in the isolation of GAD65-specific monoclonal autoantibodies
Autoantibodies against antigens expressed by insulin-producing β cells are circulating in both healthy individuals and patients at risk of developing Type 1 diabetes. Recent studies suggest that another set of antibodies (anti-idiotypic antibodies) exists in this antibody/antigen interacting network...
Autores principales: | Jiang, Wei, Macmillan, Henriette, Madec, Anne-Marie, Mellins, Elizabeth D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680538/ https://www.ncbi.nlm.nih.gov/pubmed/29167731 http://dx.doi.org/10.12688/f1000research.6467.2 |
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