Cargando…

Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish

Toll-like receptor 4 (TLR4) plays a critical role in host immunity against Gram-negative bacteria. It transduces signals through two distinct TIR-domain-containing adaptors, MyD88 and TRIF, which function at the plasma membrane and endosomes, respectively. Using zebrafish Aeromonas hydrophila infect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Srivastava, Nidhi, Shelly, Asha, Kumar, Manmohan, Pant, Archana, Das, Bhabatosh, Majumdar, Tanmay, Mazumder, Shibnath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680545/ https://www.ncbi.nlm.nih.gov/pubmed/29142761 http://dx.doi.org/10.1038/cddiscovery.2017.67

Ejemplares similares

Aeromonas hydrophila inhibits autophagy triggering cytosolic translocation of mtDNA which activates the pro-apoptotic caspase-1/IL-1β-nitric oxide axis in headkidney macrophages
por: Kumar, Manmohan, et al.
Publicado: (2021)

MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosis
por: Yang, Du-Jiang, et al.
Publicado: (2022)

Beyond MyD88 and TRIF Pathways in Toll-Like Receptor Signaling
por: Piras, Vincent, et al.
Publicado: (2014)

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
por: Sakai, Jiro, et al.
Publicado: (2017)

β-Catenin Elicits Drp1-Mediated Mitochondrial Fission Activating the Pro-Apoptotic Caspase-1/IL-1β Signalosome in Aeromonas hydrophila-Infected Zebrafish Macrophages
por: Sharma, Shagun, et al.
Publicado: (2023)

MyD88 and TRIF mediate divergent inflammatory and regenerative responses to skeletal muscle ischemia
por: Sachdev, Ulka, et al.
Publicado: (2014)

Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice
por: Heuss, Neal D, et al.
Publicado: (2014)

Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes
por: Androulidaki, Ariadne, et al.
Publicado: (2018)

MyD88 But Not TRIF Is Essential for Osteoclastogenesis Induced by Lipopolysaccharide, Diacyl Lipopeptide, and IL-1α
por: Sato, Nobuaki, et al.
Publicado: (2004)

Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways
por: Pang, Zheng, et al.
Publicado: (2018)

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF
por: Semple, Fiona, et al.
Publicado: (2011)

Neutrophil recruitment and activation are differentially dependent on MyD88/TRIF and MAVS signaling during RSV infection
por: Kirsebom, Freja C. M., et al.
Publicado: (2019)

TLR22-Induced Pro-Apoptotic mtROS Abets UPR(mt)-Mediated Mitochondrial Fission in Aeromonas hydrophila-Infected Headkidney Macrophages of Clarias gariepinus
por: Kumar, Manmohan, et al.
Publicado: (2022)

Mechanism of focal cerebral ischemic tolerance in rats with ischemic preconditioning involves MyD88- and TRIF-dependent pathways
por: LI, HAN, et al.
Publicado: (2013)

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage
por: Lin, Sen, et al.
Publicado: (2012)

Immunohistochemical Analysis of Toll-Like Receptors, MyD88, and TRIF in Human Papillary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma
por: Nihon-Yanagi, Yasuhiro, et al.
Publicado: (2021)

MyD88-dependent Dendritic and Epithelial Cell Crosstalk Orchestrates Immune Responses to Allergens
por: Thomas, Seddon Y., et al.
Publicado: (2017)

Ameliorating ER-stress attenuates Aeromonas hydrophila-induced mitochondrial dysfunctioning and caspase mediated HKM apoptosis in Clarias batrachus
por: Banerjee, Chaitali, et al.
Publicado: (2014)

MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity
por: Saikh, Kamal U.
Publicado: (2021)

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
por: Luo, Wu, et al.
Publicado: (2022)

Induction of TRIF- or MYD88-dependent pathways perturbs cell cycle regulation in pancreatic cancer
por: Zambirinis, Constantinos P., et al.
Publicado: (2013)

The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
por: Pereira, Milton, et al.
Publicado: (2022)

A MyD88 meddles with survival
por: Bashyam, Hema
Publicado: (2007)

Role of MyD88 in Adenovirus Keratitis
por: Zhou, Xiaohong, et al.
Publicado: (2016)

Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer
por: Chuffa, Luiz Gustavo A, et al.
Publicado: (2015)

Simvastatin improves cerebrovascular injury caused by ischemia-reperfusion through NF-κB-mediated apoptosis via MyD88/TRIF signaling
por: Chen, Zhiying, et al.
Publicado: (2018)

Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop
por: Liang, Shuang, et al.
Publicado: (2019)

Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88
por: Zhang, Huajia, et al.
Publicado: (2016)

Role of Calmodulin-Calmodulin Kinase II, cAMP/Protein Kinase A and ERK 1/2 on Aeromonas hydrophila-Induced Apoptosis of Head Kidney Macrophages
por: Banerjee, Chaitali, et al.
Publicado: (2014)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

Membrane Vesicles Derived From Clostridium botulinum and Related Clostridial Species Induce Innate Immune Responses via MyD88/TRIF Signaling in vitro
por: Kobayashi, Nobuhide, et al.
Publicado: (2022)

Surface immunogenic protein from Streptococcus agalactiae and Fissurella latimarginata hemocyanin are TLR4 ligands and activate MyD88- and TRIF dependent signaling pathways
por: Díaz-Dinamarca, Diego A., et al.
Publicado: (2023)

MyD88 contribution to ocular surface homeostasis
por: Reins, Rose Y., et al.
Publicado: (2017)

Mechanism of MyD88S mediated signal termination
por: Pustelny, Katarzyna, et al.
Publicado: (2022)

A Novel Kindred with MyD88 Deficiency
por: Bucciol, Giorgia, et al.
Publicado: (2022)

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
por: Livraghi-Butrico, Alessandra, et al.
Publicado: (2012)

MyD88 and TRIF mediate the cyclic adenosine monophosphate (cAMP) induced corticotropin releasing hormone (CRH) expression in JEG3 choriocarcinoma cell line
por: Uh, Andy, et al.
Publicado: (2009)

Identification and Function of Myeloid Differentiation Factor 88 (MyD88) in Litopenaeus vannamei
por: Zhang, Shuang, et al.
Publicado: (2012)

MyD88 Polymorphisms and Association with Susceptibility to Salmonella Pullorum
por: Liu, Xian-Qing, et al.
Publicado: (2015)

Interplay Between Sialic Acids, Siglec-E, and Neu1 Regulates MyD88- and TRIF-Dependent Pathways for TLR4-Activation During Leishmania donovani Infection
por: Karmakar, Joyshree, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tljtpcst6jnkbfcto9ajgvh5or