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Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fission

Mitochondria form highly dynamic networks in which organelles constantly fuse and divide. The relevance of mitochondrial dynamics is evident from its implication in various human pathologies, including cancer or neurodegenerative, endocrine and cardiovascular diseases. Dynamin-related protein 1 (DRP...

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Detalles Bibliográficos
Autores principales: Rehklau, Katharina, Hoffmann, Lena, Gurniak, Christine B, Ott, Martin, Witke, Walter, Scorrano, Luca, Culmsee, Carsten, Rust, Marco B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680571/
https://www.ncbi.nlm.nih.gov/pubmed/28981113
http://dx.doi.org/10.1038/cddis.2017.448