Cargando…
Cholera host response gene networks: preliminary studies
Gene network analysis was performed based on published literature describing genes that are possibly interconnected with cholera vaccine responses in vitro in cell culture and in vivo in human patient punch biopsies as well as DNA extracted from blood. These studies produced divergent results. The d...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680717/ https://www.ncbi.nlm.nih.gov/pubmed/29162968 http://dx.doi.org/10.6026/97320630013347 |
_version_ | 1783277817331449856 |
---|---|
author | Shapshak, Paul Somboonwit, Charurut Cao, Shu Sinnott, John T. |
author_facet | Shapshak, Paul Somboonwit, Charurut Cao, Shu Sinnott, John T. |
author_sort | Shapshak, Paul |
collection | PubMed |
description | Gene network analysis was performed based on published literature describing genes that are possibly interconnected with cholera vaccine responses in vitro in cell culture and in vivo in human patient punch biopsies as well as DNA extracted from blood. These studies produced divergent results. The differences should be replicated and studied further. Included in such studies, patient ethnicities, states of stress, nutrition, and health, as well as the precise characteristics of the various cholera vaccines and modes of delivery need to be considered as well. |
format | Online Article Text |
id | pubmed-5680717 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-56807172017-11-21 Cholera host response gene networks: preliminary studies Shapshak, Paul Somboonwit, Charurut Cao, Shu Sinnott, John T. Bioinformation Hypothesis Gene network analysis was performed based on published literature describing genes that are possibly interconnected with cholera vaccine responses in vitro in cell culture and in vivo in human patient punch biopsies as well as DNA extracted from blood. These studies produced divergent results. The differences should be replicated and studied further. Included in such studies, patient ethnicities, states of stress, nutrition, and health, as well as the precise characteristics of the various cholera vaccines and modes of delivery need to be considered as well. Biomedical Informatics 2017-10-31 /pmc/articles/PMC5680717/ /pubmed/29162968 http://dx.doi.org/10.6026/97320630013347 Text en © 2017 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |
spellingShingle | Hypothesis Shapshak, Paul Somboonwit, Charurut Cao, Shu Sinnott, John T. Cholera host response gene networks: preliminary studies |
title | Cholera host response gene networks: preliminary studies |
title_full | Cholera host response gene networks: preliminary studies |
title_fullStr | Cholera host response gene networks: preliminary studies |
title_full_unstemmed | Cholera host response gene networks: preliminary studies |
title_short | Cholera host response gene networks: preliminary studies |
title_sort | cholera host response gene networks: preliminary studies |
topic | Hypothesis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680717/ https://www.ncbi.nlm.nih.gov/pubmed/29162968 http://dx.doi.org/10.6026/97320630013347 |
work_keys_str_mv | AT shapshakpaul cholerahostresponsegenenetworkspreliminarystudies AT somboonwitcharurut cholerahostresponsegenenetworkspreliminarystudies AT caoshu cholerahostresponsegenenetworkspreliminarystudies AT sinnottjohnt cholerahostresponsegenenetworkspreliminarystudies |