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Cholera host response gene networks: preliminary studies

Gene network analysis was performed based on published literature describing genes that are possibly interconnected with cholera vaccine responses in vitro in cell culture and in vivo in human patient punch biopsies as well as DNA extracted from blood. These studies produced divergent results. The d...

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Detalles Bibliográficos
Autores principales: Shapshak, Paul, Somboonwit, Charurut, Cao, Shu, Sinnott, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680717/
https://www.ncbi.nlm.nih.gov/pubmed/29162968
http://dx.doi.org/10.6026/97320630013347
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author Shapshak, Paul
Somboonwit, Charurut
Cao, Shu
Sinnott, John T.
author_facet Shapshak, Paul
Somboonwit, Charurut
Cao, Shu
Sinnott, John T.
author_sort Shapshak, Paul
collection PubMed
description Gene network analysis was performed based on published literature describing genes that are possibly interconnected with cholera vaccine responses in vitro in cell culture and in vivo in human patient punch biopsies as well as DNA extracted from blood. These studies produced divergent results. The differences should be replicated and studied further. Included in such studies, patient ethnicities, states of stress, nutrition, and health, as well as the precise characteristics of the various cholera vaccines and modes of delivery need to be considered as well.
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spelling pubmed-56807172017-11-21 Cholera host response gene networks: preliminary studies Shapshak, Paul Somboonwit, Charurut Cao, Shu Sinnott, John T. Bioinformation Hypothesis Gene network analysis was performed based on published literature describing genes that are possibly interconnected with cholera vaccine responses in vitro in cell culture and in vivo in human patient punch biopsies as well as DNA extracted from blood. These studies produced divergent results. The differences should be replicated and studied further. Included in such studies, patient ethnicities, states of stress, nutrition, and health, as well as the precise characteristics of the various cholera vaccines and modes of delivery need to be considered as well. Biomedical Informatics 2017-10-31 /pmc/articles/PMC5680717/ /pubmed/29162968 http://dx.doi.org/10.6026/97320630013347 Text en © 2017 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Hypothesis
Shapshak, Paul
Somboonwit, Charurut
Cao, Shu
Sinnott, John T.
Cholera host response gene networks: preliminary studies
title Cholera host response gene networks: preliminary studies
title_full Cholera host response gene networks: preliminary studies
title_fullStr Cholera host response gene networks: preliminary studies
title_full_unstemmed Cholera host response gene networks: preliminary studies
title_short Cholera host response gene networks: preliminary studies
title_sort cholera host response gene networks: preliminary studies
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680717/
https://www.ncbi.nlm.nih.gov/pubmed/29162968
http://dx.doi.org/10.6026/97320630013347
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