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Sequence analysis and characterization of pyruvate kinase from Clonorchis sinensis, a 53.1-kDa homopentamer, implicated immune protective efficacy against clonorchiasis
BACKGROUND: Clonorchis sinensis, the causative agent of clonorchiasis, is classified as one of the most neglected tropical diseases and affects more than 15 million people globally. This hepatobiliary disease is highly associated with cholangiocarcinoma. As key molecules in the infectivity and subsi...
Autores principales: | Chen, Tingjin, Jiang, Hongye, Sun, Hengchang, Xie, Zhizhi, Ren, Pengli, Zhao, Lu, Dong, Huimin, Shi, Mengchen, Lv, Zhiyue, Wu, Zhongdao, Li, Xuerong, Yu, Xinbing, Huang, Yan, Xu, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680780/ https://www.ncbi.nlm.nih.gov/pubmed/29121987 http://dx.doi.org/10.1186/s13071-017-2494-9 |
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