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Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo
BACKGROUND: The Democratic Republic of the Congo (DRC) bears a large share of global malaria burden despite efforts to control and eliminate the disease. More detailed understanding of individual and household level characteristics associated with malaria are needed, as is an understanding of how th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680818/ https://www.ncbi.nlm.nih.gov/pubmed/29121931 http://dx.doi.org/10.1186/s12936-017-2110-7 |
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author | Mwandagalirwa, Melchior Kashamuka Levitz, Lauren Thwai, Kyaw L. Parr, Jonathan B. Goel, Varun Janko, Mark Tshefu, Antoinette Emch, Michael Meshnick, Steven R. Carrel, Margaret |
author_facet | Mwandagalirwa, Melchior Kashamuka Levitz, Lauren Thwai, Kyaw L. Parr, Jonathan B. Goel, Varun Janko, Mark Tshefu, Antoinette Emch, Michael Meshnick, Steven R. Carrel, Margaret |
author_sort | Mwandagalirwa, Melchior Kashamuka |
collection | PubMed |
description | BACKGROUND: The Democratic Republic of the Congo (DRC) bears a large share of global malaria burden despite efforts to control and eliminate the disease. More detailed understanding of individual and household level characteristics associated with malaria are needed, as is an understanding of how these characteristics vary spatiotemporally and across different community-level malaria endemicities. An ongoing study in Kinshasa Province is designed to address gaps in prior malaria surveillance in the DRC by monitoring malaria across seasons, age groups and in high and low malaria sites. Across seven sites, 242 households and 1591 individuals are participating in the study. Results of the enrollment questionnaire, rapid diagnostic tests and PCR testing of dried blood spots are presented. RESULTS: Overall malaria prevalence in the study cohort is high, 27% by rapid diagnostic test and 31% by polymerase chain reaction, and malaria prevalence is highly varied across very small geographic distances. Malaria prevalence is highest in children aged 6–15. While the majority of households own bed nets, bed net usage is less than 50%. CONCLUSIONS: The study cohort will provide an understanding of how malaria persists in populations that have varying environmental exposures, varying community-level malaria, and varying access to malaria control efforts. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12936-017-2110-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5680818 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-56808182017-11-17 Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo Mwandagalirwa, Melchior Kashamuka Levitz, Lauren Thwai, Kyaw L. Parr, Jonathan B. Goel, Varun Janko, Mark Tshefu, Antoinette Emch, Michael Meshnick, Steven R. Carrel, Margaret Malar J Research BACKGROUND: The Democratic Republic of the Congo (DRC) bears a large share of global malaria burden despite efforts to control and eliminate the disease. More detailed understanding of individual and household level characteristics associated with malaria are needed, as is an understanding of how these characteristics vary spatiotemporally and across different community-level malaria endemicities. An ongoing study in Kinshasa Province is designed to address gaps in prior malaria surveillance in the DRC by monitoring malaria across seasons, age groups and in high and low malaria sites. Across seven sites, 242 households and 1591 individuals are participating in the study. Results of the enrollment questionnaire, rapid diagnostic tests and PCR testing of dried blood spots are presented. RESULTS: Overall malaria prevalence in the study cohort is high, 27% by rapid diagnostic test and 31% by polymerase chain reaction, and malaria prevalence is highly varied across very small geographic distances. Malaria prevalence is highest in children aged 6–15. While the majority of households own bed nets, bed net usage is less than 50%. CONCLUSIONS: The study cohort will provide an understanding of how malaria persists in populations that have varying environmental exposures, varying community-level malaria, and varying access to malaria control efforts. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12936-017-2110-7) contains supplementary material, which is available to authorized users. BioMed Central 2017-11-09 /pmc/articles/PMC5680818/ /pubmed/29121931 http://dx.doi.org/10.1186/s12936-017-2110-7 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Mwandagalirwa, Melchior Kashamuka Levitz, Lauren Thwai, Kyaw L. Parr, Jonathan B. Goel, Varun Janko, Mark Tshefu, Antoinette Emch, Michael Meshnick, Steven R. Carrel, Margaret Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo |
title | Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo |
title_full | Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo |
title_fullStr | Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo |
title_full_unstemmed | Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo |
title_short | Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo |
title_sort | individual and household characteristics of persons with plasmodium falciparum malaria in sites with varying endemicities in kinshasa province, democratic republic of the congo |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680818/ https://www.ncbi.nlm.nih.gov/pubmed/29121931 http://dx.doi.org/10.1186/s12936-017-2110-7 |
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