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PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC

In multiple types of tumors, fibrotic collagen is regarded as the 'highway' for cancer cell migration, which is mainly modified by lysyl hydroxylase 2 (PLOD2). The previous findings have demonstrated that the expression of PLOD2 was regulated by multiple factors, including HIF-1α, TGF-β an...

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Detalles Bibliográficos
Autores principales: Du, Hongzhi, Chen, Yulong, Hou, Xiaoying, Huang, Yue, Wei, Xiaohui, Yu, Xiaowen, Feng, Shuyun, Wu, Yao, Zhan, Meixiao, Shi, Xin, Lin, Sensen, Lu, Ligong, Yuan, Shengtao, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680920/
https://www.ncbi.nlm.nih.gov/pubmed/29072684
http://dx.doi.org/10.1038/cddis.2017.553