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HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development
Oriented cell division is one mechanism progenitor cells use during development and to maintain tissue homeostasis. Common to most cell types is the asymmetric establishment and regulation of cortical NuMA-dynein complexes that position the mitotic spindle. Here, we discover that HMMR acts at centro...
Autores principales: | Connell, Marisa, Chen, Helen, Jiang, Jihong, Kuan, Chia-Wei, Fotovati, Abbas, Chu, Tony LH, He, Zhengcheng, Lengyell, Tess C, Li, Huaibiao, Kroll, Torsten, Li, Amanda M, Goldowitz, Daniel, Frappart, Lucien, Ploubidou, Aspasia, Patel, Millan S, Pilarski, Linda M, Simpson, Elizabeth M, Lange, Philipp F, Allan, Douglas W, Maxwell, Christopher A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681225/ https://www.ncbi.nlm.nih.gov/pubmed/28994651 http://dx.doi.org/10.7554/eLife.28672 |
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